Encoraf — Encorafenib 75 mg, 90 pcs, Everest

Encoraf Capsules — Encorafenib 75 mg (90 Caps) Everest

85460₴ 89400₴ -4% On order · from 14 days
1
Active ingredient
Encorafenib
Manufacturer
Everest
 Verify authenticity
Dosage
75 mg
Dosage form Capsules
Capsules per pack 90

Encoraf 75 mg (Encorafenib) is a potent targeted kinase inhibitor specifically designed to block the BRAF protein, serving as a generic equivalent to Braftovi. It treats cancers driven by a specific genetic mutation (BRAF V600). By inhibiting this mutated protein, the drug halts the signaling pathway that allows tumor cells to grow uncontrollably.

Manufacturer: Everest Pharmaceuticals (Bangladesh). It is almost exclusively used in combination therapy (e.g., with binimetinib for melanoma) for maximum efficacy.

Key Features:

  • ✅ Targeted Action: Specifically attacks cells with the BRAF V600 mutation.
  • ✅ Combination Power: Proven to work synergistically with MEK inhibitors (Binixen) or anti-EGFR antibodies.
  • ✅ Dosage Form: 75 mg capsules designed for daily oral administration.

Prescribed by oncologists for the treatment of adult patients with:

  • 🔹 Metastatic Melanoma:
    • With a confirmed BRAF V600E or V600K mutation.
    • Used in combination with binimetinib.
  • 🔹 Metastatic Colorectal Cancer (CRC):
    • With a BRAF V600E mutation, after prior systemic therapy.
    • Used in combination with cetuximab.

Sales Unit: Bottle containing 90 capsules (75 mg strength).

⚠️ APPLICATION INSTRUCTIONS:

  • Standard Dosage (Melanoma): 450 mg (6 capsules of 75 mg) taken orally once daily.
  • Standard Dosage (Colorectal Cancer): 300 mg (4 capsules of 75 mg) taken orally once daily.
  • Administration: Take at the same time each day. Swallow whole with water. Can be taken with or without food.
  • 🚫 Dietary Restriction: Do NOT consume grapefruit or grapefruit juice (risk of toxicity).
  • ✋ Missed Dose: If the missed dose is within 12 hours of the scheduled time, take it. If more than 12 hours have passed, skip it. Do not double up.

  • ⛔ Pregnancy & Breastfeeding: Strictly contraindicated (teratogenic).
  • Hypersensitivity to Encorafenib.
  • Wild-type BRAF: Not for use in patients without the specific BRAF mutation.
  • Severe cardiac or hepatic impairment.

Treatment requires regular dermatological checks and ECG monitoring. Potential side effects include:

  • 🦴 Musculoskeletal: Arthralgia (joint pain), myopathy.
  • 🤢 Gastrointestinal: Nausea, vomiting, abdominal pain, constipation.
  • 🧴 Skin: Rash, pruritus, hyperkeratosis (thickening of skin), hand-foot syndrome.
  • 💤 General: Fatigue, fever (pyrexia).
  • ❤️ Cardiac: QT interval prolongation.
  • 👁️ Ocular: Uveitis/Iritis (eye inflammation).
On order · from 14 days
100% original product
Delivery across Ukraine
1

Notice. The information on this page is for reference only and does not replace medical consultation. Always consult a healthcare professional and read the manufacturer's instructions before using any medicine. Self-medication may be dangerous. Information updated: 15.10.2026

Customer reviews

What Customers Say

No reviews yet

Your review can be the first!

Contact us

Choose a convenient way to contact

We work daily from 9:00 to 20:00