Testoheal — Testosterone Undecanoate 40 mg, 30 Capsules

Testoheal is supplied in soft gelatin capsule form for oral administration.

Qualitative and Quantitative Composition per Capsule:

• • Active Ingredient: Testosterone Undecanoate — 40 mg.
• • Excipients: Capsule shell components (gelatin, glycerol, purified water), carrier oil matrix for enhanced lipid absorption.

Packaging Configuration: Oval-shaped soft capsules filled with yellowish oily solution. Packed in 10-count blister strips made of PVC and aluminium foil. The outer carton contains 3 blisters (total 30 capsules, labeled as "3 x 10 Capsules"). The carton features the Healing Pharma logo, prescription symbol (Rx), and product branding.

Pharmacodynamics:
Testosterone undecanoate is an ester of the natural male sex hormone testosterone. Exogenous testosterone binds to androgen receptors, stimulating gene expression responsible for the development and maintenance of male primary and secondary sexual characteristics, as well as protein synthesis and anabolism in skeletal muscle and bone tissue. It provides negative feedback regulation on gonadotropins when endogenous production is inadequate.

Pharmacokinetics:

• • Absorption: Orally administered testosterone undecanoate is absorbed from the gastrointestinal tract along with dietary lipids via the lymphatic system, avoiding rapid first-pass liver degradation.
• • Metabolism: During absorption and systemic circulation, the ester is cleaved to release free testosterone. It is primarily metabolized in the liver and peripheral tissues into classical androgenic metabolites (dihydrotestosterone, androstanediol).
• • Elimination: Metabolites are excreted mainly through urine (approx. 90%) as glucuronide and sulfate conjugates, with a minor fraction eliminated via feces.

Testoheal is indicated for adult men as hormone replacement therapy (HRT) for conditions associated with primary and secondary hypogonadism:

• • Congenital or acquired primary and secondary hypogonadism.
• • Age-related androgen deficiency in aging males (late-onset hypogonadism) accompanied by clinical symptoms such as reduced libido, fatigue, depressive moods, and muscle wasting.
• • Impotence and sexual dysfunction of endocrine origin.

Treatment with Testoheal must be prescribed and monitored exclusively by a qualified physician (endocrinologist or urologist) following confirmed laboratory blood tests for low testosterone.

Method of Administration:
Capsules must be swallowed whole with an adequate amount of water. Chewing, crushing, or breaking the capsules is strictly prohibited, as it compromises the lymphatic absorption mechanism. It is recommended to take the capsules during or immediately following a meal containing moderate fat content to maximize bioavailability.

Dosing Regimen:
Dosage is individualized. Typically, the initial daily dose ranges from 120 mg to 160 mg (3 to 4 capsules daily) for the first 2 to 3 weeks, followed by a maintenance dose ranging from 40 mg to 120 mg daily (1 to 3 capsules), divided into two intakes (morning and evening).

Administration of Testoheal is contraindicated in the following conditions:

• • Prostate or Breast Cancer: Known or suspected carcinoma of the prostate or male breast.
• • Hypersensitivity: Known hypersensitivity to testosterone, undecanoic acid, or any inactive excipient.
• • Liver Tumors: History of liver tumors (benign or malignant).
• • Female Gender: Strictly contraindicated in women, particularly during pregnancy and breastfeeding, due to the risk of fetal virilization.
• • Severe Pathologies: Severe cardiac, hepatic, or renal impairment.

Potential drug interactions should be evaluated when administering Testoheal:

• • Hepatic Enzyme Inducers (barbiturates, carbamazepine, rifampicin, phenytoin): Can decrease plasma testosterone concentrations by accelerating hepatic clearance.
• • Oral Anticoagulants: Androgens may potentiate the anticoagulant effect of coumarin derivatives, requiring dose adjustment and prothrombin time monitoring.
• • Antidiabetic Agents and Insulin: Androgens may improve glucose tolerance and decrease insulin requirements in diabetic patients.
• • ACTH or Corticosteroids: Concurrent administration increases the risk of edema formation.

Pregnancy and Lactation:
Testoheal is intended exclusively for male use and is strictly contraindicated in women. Testosterone exhibits significant virilizing effects on the fetus and can cause irreversible developmental abnormalities in female fetuses. Women of childbearing potential must avoid direct contact with damaged or ruptured capsules.

Exogenous testosterone therapy may cause the following adverse reactions:

• • Skin and Subcutaneous Tissue: Acne, seborrhea, increased body hair growth, pruritus.
• • Endocrine & Reproductive Systems: Priapism, frequent or persistent erections, decreased seminal volume, suppression of spermatogenesis, gynecomastia.
• • Metabolism and Blood: Sodium and water retention, peripheral edema, polycythemia (elevated red blood cell count and hematocrit).
• • Gastrointestinal Tract: Abdominal discomfort, nausea, diarrhea (associated with improper administration).
• • Psychiatric Disorders: Changes in libido, mood swings, increased aggression or irritability.

Symptoms:
Acute overdose with oral testosterone is unlikely. Chronic high-dose administration may result in pronounced adverse effects such as severe suppression of spermatogenesis, priapism, fluid retention, marked polycythemia, and symptoms of androgen excess.

Treatment:
Discontinue drug administration temporarily in case of overdose. Provide supportive and symptomatic care. No specific antidote exists.

Storage Requirements for Testoheal:

• 🌡️ Temperature Range: Store in a dry place protected from light at temperatures not exceeding 25–30 °C. Do not freeze.
• ☀️ Environmental Protection: Store in original manufacturer packaging to protect from moisture.
• 👶 Safety Precautions: Keep out of reach of children.
• ⏳ Shelf Life: Stated on the outer carton and blister foil. Do not use past expiration date. Prescription-only medicine.

To verify the authenticity of original Testoheal manufactured by Healing Pharma, check the following visual security elements:

• ✅ Manufacturer Logo: Official Healing Pharma logo featuring an orange-green flower/leaf icon alongside the brand name and "Your health is our world" slogan.
• ✅ Product Branding: The brand name "TESTOHEAL" printed in bold dark blue lettering, with Hindi script subtext ("टेस्टोहील").
• ✅ Carton Layout: Clean white box background accented with a characteristic blue and gold horizontal stripe pattern across the lower section.
• ✅ Pack Specifications: "3 x 10 Capsules" text layout displayed in the upper right corner, with the "Rx" prescription symbol in the upper left.
• ✅ Capsule Appearance: Soft gelatin capsules featuring a uniform oval shape and transparent yellowish oily fill.